>
> Scientists look to natural compounds in fruits and
> vegetables to win the war against cancer
>
> Natural anti-fungal compounds found on common fruits
> and vegetables could unlock the belly of a Trojan
> horse lying latent inside cancer cells. Laboratory
> tests have shown that the compounds, called
> salvestrols, unleash a potent army of snipers that
> pick off cancer cells without harming normal cells.
>
> A small team of pharmacologists and bio-chemists in
> England discovered the compounds almost four years
> ago, and say they are an example of the potential
> power of orthomolecular, or nutrition-based, medicine
> even though it has only been tested in the lab.
>
> About 250 orthomolecular practitioners from 14
> countries will gather in Vancouver this weekend for
> the 37th annual international conference on the
> biochemical approach to health.
>
> Orthomolecular medicine, meaning the right molecule,
> argues that diseases are caused by chemical imbalances
> in the body and that they can be corrected using
> vitamins, minerals and amino acids.
>
> The approach is still disputed by many in conventional
> medicine, including the respected Cochrane Library,
> which recently reviewed the literature on antioxidants
> and found no evidence to support their use for
> prevention.
>
> But nutrition therapy has gained some credence lately
> because of a growing body of evidence demonstrating
> the value of food and food derivatives such as
> omega-3s and Vitamin D to prevent and heal disease.
>
> In the case of the anti-fungal compounds, its
> proponents are convinced their presence or absence in
> diet could help explain why some people get cancer and
> some don't. They also believe it is a potent cancer
> fighting therapy.
>
> The as yet unproven therapy was discovered after Dan
> Burke, a former University of Aberdeen toxicologist
> and pharmaceutical metabolism professor who found an
> enzyme called CYP1B1 (pronounced sip one bee one) that
> is present in all cancer cells but absent in all
> non-cancerous cells.
>
> A mainstream cancer researcher for 30 years, Burke
> knew he'd stumbled onto something big.
>
> The problem with cancer is that unlike many diseases,
> it has no alien source -- no infection or bacteria
> towards which treatment can be directed.
>
> Cancer cells are normal cells that don't die. They
> just multiply forever. So current treatments, such as
> chemotherapy and radiation, can't target just the
> cancerous cells.
>
> They can only carpet bomb the cancerous area,
> destroying normal cells in the process and causing
> immune deficiency, hair loss and other unpleasant side
> effects.
>
> In his enzyme, Burke had a target that drugs could
> attack. He and colleague Gerry Potter, a professor of
> medicinal chemistry with a long history of developing
> anti-cancer drugs, began preliminary research into
> creating a pro-drug, a drug that can enter all cells
> but is harmless until it encounters the CYP1B1 enzyme.
>
> "CYP1B1 is a Trojan horse," Burke said in a recent
> Vancouver interview. "It is intrinsic in cancer cells.
> All you have to do is give it [a pro-drug] and it will
> unleash the armies to kill the cancers cells."
>
> Source: canada.com
>
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