Thank you so much for this source. I can't wait
to show it to my onc and hear her response to it.
Angel
From: "Dave"
Angel, it's more like 2.3% or less
Report comes from a group of oncologists in Australia who studied the
matter for several years, and came to the conclusion that chemo itself
is at most 2.3 % (etc) effective.
It's available in the medical archives in the US, but you didn't read it in any US newspapers.
Here is the summary..
This message contains search results from the National Center for
Biotechnology Information (NCBI <http://www.ncbi.nlm.nih.gov>) at the
U.S. National Library of Medicine (NLM <http://www.nlm.nih.gov>). Do not reply directly to this message
Department of Radiation Oncology, Northern Sydney Cancer Centre,
Royal North Shore Hospital, Sydney, NSW, Australia.
gmorgan1@bigpond.net.au
AIMS: The debate on the funding and availability of cytotoxic drugs raises questions about the contribution of curative or adjuvant
cytotoxic chemotherapy to survival in adult cancer patients.
MATERIALS AND METHODS: We undertook a literature search for
randomised clinical trials reporting a 5-year survival benefit
attributable solely to cytotoxic chemotherapy in adult malignancies.
The total number of newly diagnosed cancer patients for 22 major
adult malignancies was determined from cancer registry data in
Australia and from the Surveillance Epidemiology and End Results
data in the USA for 1998. For each malignancy,
the absolute number to benefit was the product of (a) the total
number of persons with that malignancy; (b) the proportion or
subgroup(s) of that malignancy showing a benefit; and (c) the
percentage increase in 5-year survival due solely to cytotoxic
chemotherapy. The overall contribution was the sum total of the absolute numbers showing a 5-year survival benefit expressed as a
percentage of the total number for the 22 malignancies. RESULTS: The
overall contribution of curative and adjuvant cytotoxic chemotherapy
to 5-year survival in adults was estimated to be 2.3% in Australia
and 2.1% in the USA.
CONCLUSION: As the 5-year relative survival rate for cancer in
Australia is now over 60%, it is clear that cytotoxic chemotherapy
only makes a minor contribution to cancer survival. To justify the
continued funding and availability of drugs used in cytotoxic
chemotherapy, a rigorous evaluation of the cost-effectiveness and
impact on quality of life is urgently required.
PMID: 15630849 [PubMed - indexed for MEDLINE]
Entrez PubMed Results
Item 1 of 1
*1: *Clin Oncol (R Coll Radiol). 2004
Dec;16(8):549-60.Cited in PMC
<http://www.pubmedcentral.gov/tocrender.fcgi?action=cited&tool=pubmed&pubmedid=15630849&itool=Email.EmailReport.Pubmed_ReportSelector.Pubmed_HVAbstractPlus&ordinalpos=1>,
LinkOut
<http://www.ncbi.nlm.nih.gov/sites/entrez?Cmd=ShowLinkOut&Db=PubMed&TermToSearch=15630849&ordinalpos=1&itool=Email.EmailReport.Pubmed_ReportSelector.Pubmed_HVAbstractPlus>
Comment in:
Clin Oncol (R Coll Radiol). 2005
Jun;17(4):294.
The contribution of cytotoxic chemotherapy
to 5-year survival in adult malignancies.
*Morgan G*
------------------------------------
Yahoo! Groups Links
<*> To visit your group on the web, go to:
http://groups.yahoo.com/group/cancercured/
<*> Your email settings:
Individual Email | Traditional
<*> To change settings online go to:
http://groups.yahoo.com/group/cancercured/join
(Yahoo! ID required)
<*> To change settings via email:
mailto:cancercured-digest@yahoogroups.com
mailto:cancercured-fullfeatured@yahoogroups.com
<*> To unsubscribe from this group, send an email to:
cancercured-unsubscribe@yahoogroups.com
<*> Your use of Yahoo! Groups is subject to:
Tidak ada komentar:
Posting Komentar