[cancercured] Metronomic /Re: Need Input

have you looked into metronomic, low dose, chemo?
carla

Metronomic therapy for breast cancer.Kaur H, Budd GT.
Department of Hematology/Oncology, Taussig Cancer Center, The
Cleveland Clinic Foundation, R35, 9500 Euclid Avenue, Cleveland, OH
44195, USA.

Conventional cytotoxic chemotherapeutic drugs treat cancer either by
direct killing or by inhibition of growth of cycling tumor cells. In
addition, evidence suggests that cytotoxic agents may inhibit tumor
growth through an antiangiogenic mechanism. "Metronomic" or frequent
continuous administration of the same chemotherapeutic agents at
lower doses may optimize their antiangiogenic properties. The
effectiveness of metronomic chemotherapy regimens can be improved
significantly by concurrent administration of antiangiogenic,
endothelial-specific drugs. Preclinical studies have shown that
integrating chemotherapy with antiangiogenic drugs can improve
efficacy and circumvent the toxicity and drug resistance associated
with standard or high-dose chemotherapy. Preliminary clinical studies
have shown similar results. Further confirmation of this concept is
required with randomized, controlled clinical trials.

PMID: 14664761 [PubMed - indexed for MEDLINE]

"Turmeric4" <ggabrielson@...> wrote:
I have Stage IV breast cancer with mets to the bones. I have been
> doing alternative for one year. Now the cancer is in my lymph nodes in my chest and it is closing the Superior Vena Cava that drains blood from my head. I have been having pressure in my head and lots of coughing for the past four months, so that is why.
> I have wanted to avoid chemo and have never had it, but at this
point I don't think I have a choice....
> My question is: What can I do to alleviate the bad symptoms of
chemo while I am taking it. Any particular supplements, etc. I would really appreciate advice in this area - especialy anyone who has gone through chemo and found supplements or whatever that helped a great deal.
> Thank You,
> Karen
>

------------------------------------

Yahoo! Groups Links

<*> To visit your group on the web, go to:

http://groups.yahoo.com/group/cancercured/

<*> Your email settings:
Individual Email | Traditional

<*> To change settings online go to:

http://groups.yahoo.com/group/cancercured/join

(Yahoo! ID required)

<*> To change settings via email:
mailto:cancercured-digest@yahoogroups.com
mailto:cancercured-fullfeatured@yahoogroups.com

<*> To unsubscribe from this group, send an email to:
cancercured-unsubscribe@yahoogroups.com

<*> Your use of Yahoo! Groups is subject to:

http://docs.yahoo.com/info/terms/