analog in the treatment of lymphoproliferative disorders"
wrote:
"somatostatin is a cyclic tetradecapeptide that is highly
concentrated in the hypothalamus and pancreas.......it has the
ability
to inhibit the release of many hormones and neurotransmitters.......
(....) Although the exact mechanism of action in the
lymphoproliferative disorders is unclear, several are possible.
Somatostatin could inhibit a growth hormone or factors for
malignant lymphocytes, inhibit angiogenesis, alter natural-killer
cell activity or have a direct antimitotic effect mediated
through somatostatin receptors.."
I have to add that my husband is not "cured" but the disease
is stable without toxic chemo...and without the mouse proteins
of the murine monoclonal antibody rituxan...
od course, if the somatostatin will stop working, he'll change
his treatment programs...
"breathedeepnow" <aug20> wrote:
> Hi, Carla.
> Thank you very much for this information and congratulations that
> your husband is able to control the lymphoma with somatostatin
> injections.
> I would be grateful if you could explain in lay terms just what
> somatostatin is and how it works. I did an internet search
> under "somatostatin lymphoma" but all I found was technical stuff
> which, when I read it, made it look as if somatostatins bind to
> lymphoma cells, but that it is other things attached to the
> somatostatins that actually destroy the cancer.
> I hope you can enlighten me in terms I can understand about how
> somatostatins work, or else direct me to a site where I can read a
> lay explanation about somatostatins. Thanks so much. Elliot
>
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