with cytotoxic therapies, the control was likely standard therapy
(also cytotoxics) ...
I think we should acknowledge the limitations of studies that look at
cancer as if it's one disease, because each type is unique and the
risks and benefits of standard therapies vary enourmously for each.
For example, Hodgkins lymphoma is 80% curable with standard
therapies. Childhood cancers versus adult types ... etc. Stage of
disease also matters a great deal as to how effective standard
therapies can be.
All that said, there's a need for more effective therapies for
different cancerrs with greater specificity to cancer cells.
Just my two cents.
~ Karl
> Angel, it's more like 2.3% or less
>
> Report comes from a group of oncologists in Australia who studied
the matter for several years, and came to the conclusion that chemo
itself is at most 2.3 % (etc) effective.
It's available in the medical archives in the US, but you didn't
read it in any US newspapers.
>
> Dave
>
> Here is the summary..
> ======= ============= ============= =================
>
> This message contains search results from the National Center for
> Biotechnology Information (NCBI <http://www.ncbi.nlm.nih.gov>) at
the
> U.S. National Library of Medicine (NLM <http://www.nlm.nih.gov>).
Do not
> reply directly to this message
>
> *Sender's message:* Dave Chemo ineffective
>
> Sent on: Thu Dec 13 20:51:42 2007
> Select 15630849
>
> Department of Radiation Oncology, Northern Sydney Cancer Centre,
> Royal North Shore Hospital, Sydney, NSW, Australia.
> gmorgan1@...
>
> AIMS: The debate on the funding and availability of cytotoxic
drugs
> raises questions about the contribution of curative or adjuvant
> cytotoxic chemotherapy to survival in adult cancer patients.
> MATERIALS AND METHODS: We undertook a literature search for
> randomised clinical trials reporting a 5-year survival benefit
> attributable solely to cytotoxic chemotherapy in adult
malignancies.
> The total number of newly diagnosed cancer patients for 22 major
> adult malignancies was determined from cancer registry data in
> Australia and from the Surveillance Epidemiology and End Results
> data in the USA for 1998. For each malignancy, the absolute
number
> to benefit was the product of (a) the total number of persons
with
> that malignancy; (b) the proportion or subgroup(s) of that
> malignancy showing a benefit; and (c) the percentage increase in
> 5-year survival due solely to cytotoxic chemotherapy. The
overall
> contribution was the sum total of the absolute numbers showing a
> 5-year survival benefit expressed as a percentage of the total
> number for the 22 malignancies. RESULTS: The overall
contribution of
> curative and adjuvant cytotoxic chemotherapy to 5-year survival
in
> adults was estimated to be 2.3% in Australia and 2.1% in the
USA.
> CONCLUSION: As the 5-year relative survival rate for cancer in
> Australia is now over 60%, it is clear that cytotoxic
chemotherapy
> only makes a minor contribution to cancer survival. To justify
the
> continued funding and availability of drugs used in cytotoxic
> chemotherapy, a rigorous evaluation of the cost-effectiveness
and
> impact on quality of life is urgently required.
>
> PMID: 15630849 [PubMed - indexed for MEDLINE]
>
>
> Entrez PubMed Results
>
> Item 1 of 1
>
> *1: *Clin Oncol (R Coll Radiol). 2004 Dec;16(8):549-60.Cited in PMC
> <http://www.pubmedcentral.gov/tocrender.fcgi?
action=cited&tool=pubmed&pubmedid=15630849&itool=Email.EmailReport.Pub
med_ReportSelector.Pubmed_HVAbstractPlus&ordinalpos=1>,
> LinkOut
> <http://www.ncbi.nlm.nih.gov/sites/entrez?
Cmd=ShowLinkOut&Db=PubMed&TermToSearch=15630849&ordinalpos=1&itool=Ema
il.EmailReport.Pubmed_ReportSelector.Pubmed_HVAbstractPlus>
>
> Comment in:
> Clin Oncol (R Coll Radiol). 2005 Jun;17(4):294.
>
> <http://www.ncbi.nlm.nih.gov/sites/entrez?
Db=PubMed&Cmd=ShowDetailView&TermToSearch=15997929&ordinalpos=1&itool=
Email.EmailReport.Pubmed_ReportSelector.Pubmed_HVAbstractPlus>
>
>
> The contribution of cytotoxic chemotherapy to 5-year
survival in
> adult malignancies.
>
> *Morgan G*
>
> <http://www.ncbi.nlm.nih.gov/sites/entrez?
Db=PubMed&Cmd=Search&Term=%22Morgan%20G%22%5BAuthor%
5D&itool=Email.EmailReport.Pubmed_ReportSelector.Pubmed_HVAbstractPlus
>,
> *Ward R*
>
> <http://www.ncbi.nlm.nih.gov/sites/entrez?
Db=PubMed&Cmd=Search&Term=%22Ward%20R%22%5BAuthor%
5D&itool=Email.EmailReport.Pubmed_ReportSelector.Pubmed_HVAbstractPlus
>,
> *Barton M*
>
> <http://www.ncbi.nlm.nih.gov/sites/entrez?
Db=PubMed&Cmd=Search&Term=%22Barton%20M%22%5BAuthor%
5D&itool=Email.EmailReport.Pubmed_ReportSelector.Pubmed_HVAbstractPlus
>.
>
> =========== ============= ============== ===========
> On 5/24/2008 10:40:22 PM, angel z. nest
> (toreadpeoplehealthinfo@...) wrote:
> > Hello John,
> >
> > Would you please tell me where you get this 3% cure rate figure?
> >
> > I've seen it around for a while and really would like to get my
> > oncologists input on it but must have the source/origin of this
data...
> >
> > Please tell,
> > Angel
> >
> >
> > --- In cancercured@yahoogroups.com, "John Magal" <johnmagal@>
wrote:
> > >
> > > Karl
> > > my definition of alternative medicine differs from yours; in my
book
> > > it is medicine without the use of products of the pharmaceutical
> > > indust
>
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