unfortunately:
Hoffer LJ, Levine M, Assouline S, Melnychuk D, Padayatty SJ, Rosadiuk
K, Rousseau C, Robitaille L, Miller WH Jr.
Phase I clinical trial of i.v. ascorbic acid in advanced malignancy.
Ann Oncol. 2008 Jul 25.PMID: 18544557
It should be noted:
"Only five in 5,000 compounds that enter preclinical testing make it to
human testing. One of these five tested in people is approved." ~ Food
and Drug Administration: From Test Tube to Patient
Why is the failure rate so high?
One reason is that tumors that are implanted in mice are not the same
as tumors that develop naturally in the host. Also human and mouse
biology are not the same, and tumor-host interactions are very
different. Finally responses (being active) is not the same as being
beneficial. Many treatments affect tumor growth or shrink tumors but do
not provide clinical benefit: improved survival.
Meanwhile, IV C will be attractive to many patients because ... it's a
vitamin. But vitamin C given directly into the blood at high doses
could have toxicities, or, could act as an oxidant under some
circumstances (if blood levels of iron are high for example).
~ Karl
www.lymphomation.org
--- In cancercured@yahoogroups.com, drKumar JK <drkumarj@...> wrote:
>
> We have tried high dose Vit C in some advanced cancers like
breast,colon.pancreas and lung cancers.The results are NIL.In fact it
promoted cancer growth and there are many studies to support it.We had
to stop Vit C and bring these patients back into remission.We are
convinced Vit C promotes cancer growth.Be vigilant if you vennture into
this high dose Vit C treatment.
> Kumar
>
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