High dose vitamin C injections slash tumor growth in mice
An article published in the August 5, 2008, issue of the Proceedings of
the National Academy of Sciences reported that injections of ascorbate
(vitamin C) reduce the weight and growth rate of tumors by half in mouse
models of ovarian, pancreatic and brain cancer, while leaving normal
cells unharmed.
Researchers at the National Institutes of Health (NIH) tested ascorbate
in 43 tumor and 5 normal cell lines to determine a concentration that
decreases cell survival in cancerous cells without resulting in toxicity
to healthy cells. They subsequently injected a dose of 4 grams ascorbate
(neutralized with sodium hydroxide) per kilogram body weight once or
twice per day into immune-deficient mice with implanted ovarian,
pancreatic and glioblastoma (brain) tumors. "At these high injected
doses, we hoped to see drug-like activity that might be useful in
cancer," explained lead author Mark Levine, MD, who is the chief of the
Molecular and Clinical Nutrition Section of the National Institute of
Diabetes and Digestive and Kidney Diseases at the NIH.
Dr Levine's team found that injecting the animals with ascorbate
decreased tumor growth and weight by 41 to 53 percent. While metastases
occurred in 30 percent of the mice with brain tumors, none appeared in
animals injected with vitamin C. No adverse effects of vitamin C
treatment were noted.
Continue Reading:
http://www.lef.org/newsletter/2008/0805_High-Dose-Vitamin-C-Injections-Slash-Tumor-Growth-in-Mice.htm
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