Angel
http://www.prnewswire.co.uk/cgi/news/release?id=233021
GeneNews Launches World's First Blood Test for Colorectal Cancer Screening
TORONTO, July 21 /PRNewswire/ -- GeneNews Limited (TSX: GEN), a company focused on developing blood-based biomarker tests for the early detection of diseases and personalized health management, today announced the launch of ColonSentry(TM), the world's first blood-based molecular test for colorectal cancer screening. ColonSentry(TM) is a blood test that assesses a patient's current risk of having colorectal cancer, identifying those in the asymptomatic general population with increased risk who might benefit from further more invasive diagnostic testing such as colonoscopy. This risk stratification approach allows for a more targeted application of colonoscopy which could increase the detection rate of colorectal cancer by as much as 3 fold in an asymptomatic general population. The test requires a simple blood sample. The mRNA expression of a panel of seven specific genes is measured at the molecular level by quantitative RT-PCR which results in an assessment of the patient's current risk. ColonSentry will be performed at the Company's laboratory facilities in Richmond Hill, Canada and is the first in a series of blood-based molecular tests based on the company's platform technology, the award-winning Sentinel Principle(TM).
"Each year thousands of Canadians die from colorectal cancer, the number two cause of death among all cancers in both men and women. This is a tragedy because colorectal cancer is a preventable and curable disease, but only when detected early," said Dr. Lawrence Cohen, Director of Gastroenterology at Sunnybrook Health Sciences Centre and Associate Professor of Medicine at the University of Toronto. "The launch of ColonSentry(TM) represents a leap forward in the way we currently screen for colorectal cancer. The test determines whether patients have an increased risk of having colorectal cancer. By using this risk assessment tool as the first step in a regular screening program, information obtained with ColonSentry(TM) will result in better decision making by doctors and their patients regarding next steps in the colorectal cancer screening process and ultimately help identify the presence of this cancer in patients at a curable stage."
"More than 21,500 Canadians will be diagnosed with colorectal cancer this year and most of them will not have exhibited any symptoms. The most effective method for prevention and early detection of colorectal cancer is through widespread screening of individuals," said Barry D. Stein, President of the Colorectal Cancer Association of Canada. "A patient-friendly blood test like ColonSentry(TM) is welcomed and can certainly contribute to increased compliance with screening programs. This will facilitate earlier detection and treatment of the disease, resulting in improved outcomes for patients with colorectal cancer."
"Ideally, colorectal cancer screening should proceed in a programmatic fashion that begins with risk stratification based on the results from an initial test and then continues with proper follow up based on findings," said Dr. Bernard Levin, an internationally recognized expert in colorectal cancer screening and Chair of the Company's Colorectal Cancer Clinical Advisory Board. "As the initial test, the convenience of a blood test to assess current risk could encourage more individuals to undergo screening, leading to earlier detection of colorectal cancer thereby reducing suffering and death."
"More than 1.5 million people in the GTA meet the eligibility guidelines for colorectal cancer screening, making this an ideal location for the initial launch of ColonSentry(TM). We are building our commercial organization and look forward to subsequent planned launches of ColonSentry(TM) in Asia, the United States and Europe," said Dr. Heiner Dreismann, interim CEO and Lead Director of GeneNews. "Achieving this most significant milestone well on target reflects the deep commitment of the entire GeneNews staff and the timely delivery of the first in our pipeline of innovative tests to provide actionable information for more personalized health management." The ColonSentry(TM) test can be ordered by physicians throughout the Greater Toronto Area. Additional information on the ColonSentry(TM) test can be found at http://www.colonsentry.com or by calling 1-877-GENENEWS (436-3639).
About GeneNews
GeneNews is focused on the application of functional genomics to enable early diagnosis and personalized therapeutic intervention based on disease-specific biomarkers. The Company has developed a novel approach, the Sentinel Principle(TM), to detect and stage virtually any disease or medical condition from a simple blood sample. GeneNews is currently applying the Sentinel Principle(TM) in major areas with unmet clinical needs such as cancer, arthritis, cardiovascular disease and neurological disorders. For more information on GeneNews, visit http;//www.genenews.com.
This press release contains forward-looking statements, which reflect the Company's current expectations regarding future events. The forward-looking statements involve risks and uncertainties. Actual events could differ materially from those projected herein. Investors should consult the Company's ongoing quarterly filings and annual reports for additional information on risks and uncertainties relating to these forward-looking statements. The reader is cautioned not to rely on these forward-looking statements. The Company disclaims any obligation to update these forward-looking statements.
For further information: James Smith, +1-416-815-0070 x 229, jsmith@equicomgroup.com
Distributed by PR Newswire on behalf of GeneNews Limited
--------------------------------------------------------------------------------
PR Newswire Europe Ltd.
209 - 215 Blackfriars Road, London, SE1 8NL
Tel : +44 (0)20 7490 8111
Fax : +44 (0)20 7490 1255
E-mail : info@prnewswire.co.uk
6. Will the test tell me if I have colon cancer, and is it 100% accurate?
ColonSentry assesses your current risk of having colorectal cancer. This information can determine whether you should have a colonoscopy. It does not actually diagnose the disease. This must be done with a colonoscopy. ColonSentry tells you about your risk of colorectal cancer at a given point in time. This is different than a genetic test which provides you with information about genetic predisposition, future risk or lifetime risk of developing colorectal cancer. ColonSentry is accurate about 70% of the time.
It is important to realize that this (ColonSentry) is a screening test for cancer, not polyps. The genes that are sought in blood are those commonly found in people with colorectal cancer. The test may tell you that you are at higher risk for HAVING colon cancer, not getting it in the future. It needs to be repeated regularly, although the developers are not sure how often. One "low risk" test doesn't get you off the danger hook.
Last spring three organizations collaborated to develop new screening guidelines for colorectal cancer: The American Cancer Society, US Multi-society Task Force on Colorectal Cancer, and the American College of Radiology.
http://fightcolorectalcancer.org/awareness/patients/prevention/screening
For the first time, they divided screening tests into those primarily for the early detection of cancer and those for the prevention of CRC by finding and removing precancerous polyps.
Three tests -- FOBT, FIT, and stool DNA -- were listed as those "Tests that Primarily Detect Cancer". Four -- colonoscopy, flexible sigmoidoscopy, barium enema, and CT-colonography -- were recommended as "Tests that Detect Adenomatous Polyps and Cancer"
In communities where resources for endoscopy or radiology are limited, tests that screen for colorectal cancer can prioritize those patients who need colonoscopy ASAP.
And, as Dr. Winawer says, "The best test is the test that gets done." We can debate endlessly which is the best test, but if insurance, availability of gastroenterologists, or patient unwillingness are barriers, we need the tests that will get done. Blood tests are simple, acceptable . . . but may not be cheap.
To help remove barriers to colorectal cancer testing in the US go to www.coveryourbutt.org
Kate
[Non-text portions of this message have been removed]
------------------------------------
Yahoo! Groups Links
<*> To visit your group on the web, go to:
http://groups.yahoo.com/group/cancercured/
<*> Your email settings:
Individual Email | Traditional
<*> To change settings online go to:
http://groups.yahoo.com/group/cancercured/join
(Yahoo! ID required)
<*> To change settings via email:
mailto:cancercured-digest@yahoogroups.com
mailto:cancercured-fullfeatured@yahoogroups.com
<*> To unsubscribe from this group, send an email to:
cancercured-unsubscribe@yahoogroups.com
<*> Your use of Yahoo! Groups is subject to:
http://docs.yahoo.com/info/terms/
Tidak ada komentar:
Posting Komentar