Re: [cancercured] Methylglyoxal

Jonathan,

Always keep in mind that there is a prescreening process going
on. You don't want to accept those patients for methylglyoxal who
don't seem to be good candidates, and that is most of them. There
are many reasons including: acute pathologies even if incipient
(e.g., DVT, pneumonia), volume of distribution issues in
decompensation of any essential organ system or with
ascites/effusion, chemical and strategic incompatibilities, cancers
in which it has been shown to ineffective or less effective (many
lymphomas, squamous, sarcomas, leukemias, etc.), use in patients
which with preexisting pathologies in organs that would be placed in
greater risk with methylglyoxal use (e.g., heart, kidneys, liver,
pancreas, eyesight).

Both Manju Ray and I have had success with patients who are good
candidates, but the patients must continue taking it. If
discontinued, the cancer can be expected to return as evidenced by
all tests with animal models and informal tests with humans. When
Manju last stayed out our retreat center in Del Mar, California she
said that she had one patient who stopped taking the methylglyoxal
for a year and it had not yet returned. I have used more
methylglyoxal than anyone in the western hemisphere and I have seen
stabilization of disease in many patients who are good candidates. I
have not seen any complete remissions in any patients who used it as
a standalone.

Methylglyoxal is less useful if there is drug resistance. It
can be quite useful post radiation if chemotherapy was not used. If
used wisely methylglyoxal can be quite helpful. I think knowledge of
its best use is still in its infancy. We will know much more in 5-10 years.

Vincent

At 05:40 AM 3/19/2008, you wrote:

>Hi Vincent
>
>Your comments are very interesting. You say it isn't curative. What
>about Prof Ray's first human trial which first reports said that 70%
>of the terminal patients had recovered? Also she did not seem to
>have toxicity with it - or did she?
>
>Jonathan
>
>
>
>
>VGammill <<mailto:vgammill%40adelphia.net>vgammill@adelphia.net> wrote:
>Jonathan,
>
>I don't recommend methylglyoxal for general use. There is too much
>of a risk of formaldehyde in the manufacturing process, it is easily
>oxidized, and it can be toxic. It does have its uses and I
>occasionally use it -- maybe 10% of the time. It is not curative, it
>is expensive, and there are many instances in the animal model
>research that show risk to the heart, retina, and pancreas -- all
>high-value real estate. I occasionally use mitoguazone which is a
>derivative of methylglyoxal. If used several days before IPT it
>seems to kick up the therapy.
>
>Vincent
>
>

[Non-text portions of this message have been removed]

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