>...Some chemotherapy is as distortive as treatments ever get. It is
>immunosuppressive, myelosuppressive,
>and all in all very debilitating, much more so than resveratrol and
>curcumin...
Most chemotherapy, in the usual doses, is immunosuppressive. The
devil is in the details. Vincristine is not immunsuppressive , but
vinblastine is. Bleomycin doesn't adversely affect immune
function. These chemos may have miserable and destructive side
effects, but myelosuppression is not one of them. Gemcitabine is an
antimetabolite (replacing cytidine) but it is also an immune therapy
against cancer as it suppresses splenic myeloid
cells. Cyclophosphamide is an alkylating agent in high doses but in
very low doses it is immunomodulatory. I often use it before using a
cancer vaccine.
Those chemotherapies that are myelosuppressive in the usual doses are
usually safe in IPT doses. Still they can cause multiple drug
resistance in these low doses if precautions aren't taken.
Gubi also noted the occasional salubrious effects encountered in
using seemingly contrary therapies. There are no paradoxes in nature
-- only in our minds. I often use low-dose arsenite with high-dose
ascorbate. A paradox only means one thing: you have to climb higher
on the mountain to get a better view. High dose ascorbate is
prooxidant for example. It can help kill the cancer and at the same
time (unfortunately) encourage metastasis.
I agree with Gubi in that I see no reason why resveratrol can't be
used alone with some patients. I have done the same with high-dose
tannates. The main problem is that we don't know in advance if it is
adequate. This brings up a future topic: the importance of
monitoring and assessment.
Vincent
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