Both resveratrol and curcumin are wonderful cancer-fighting tools,
but you don't use a screwdriver to pull a nail. The citation is a
great example of why you don't use the kitchen sink approach to
fighting cancer. You think things through in advance. You might
have only one opportunity to get it right.
I usually have to spend much time on this in the seminars. If you
have cancer then take it as a given that you have a significant
immune dysfunction. You can use all the immune therapies that you
can afford and still not target the problem. What if the immune
problem is due to a genetic mutation? You might have to switch up
immune strategies and use, say, humoral stimulation instead of the
usually more desirable cell-mediated approach.
If you use any of this broad family of natural chemicals, then you
are probably attenuating ALL concurrent immune approaches. Does that
mean you don't use them? Not at all. It means you have to think
through their probable mechanisms of action and choose
accordingly. Immune therapies often take months to work and they may
not work at all. You may want to choose another approach -- say, the
use of carefully selected matrix metalloproteinase/collagenase
inhibitors (perhaps including zinc chelators) within an an
overarching strategy of angiogenesis inhibition (perhaps including
copper chelators). You can use all the curcumin and resveratrol that
you want with this strategy. If you are using high doses of curcumin
or resveratrol, then the money you are spending for immune therapy
might be better spent on a more compatible strategy.
A common mistake is to OVERREAD the citation. I don't know of anyone
who became a cesspool of microbial pathogens because of using
curcumin or resveratrol. On the other hand, if you have a persistent
infection then you might consider dropping this particular whole
family of natural meds from your protocol until you sort things out.
To answer your question about flax seed oil: if you are using flax
oil as an immune therapy (and it is a corrective therapy) then you
might want to consider using it without the lignin because of the
probable immune-inhibiting properties of any ferulate. If you are
using high-dose flax seed oil as a substrate for a prooxidant or free
radical approach then you might want to drop the lignin in favor of,
say, a ferric-nitrilo strategy.
These are RARELY black-white issues and the lazy human mind loves to
think in black and white issues. We are talking about probable
additive or subtractive effects. I have seen many people use
high-lignin flax seed oil and they did just fine.
Vincent
At 06:38 AM 3/22/2008, you wrote:
>VGammill <vgammill@...> wrote:
> >
> <http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1810449>http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1810449
> > ...imperative to steer clear of the shoals of the stilbenes and
> > so many of the trans-cinnamic acid derivatives. This would include
> > DES for prostate cancer, rosmarinic acid, caffeic acid phenethyl
> > ester, and perhaps many of the gallates and tannates
>
>Any commonly used natural supplements that should therefore should be
>avoided in cases of prostate or other cancers?
>
> > It will certainly change my past recommendation of the
> > high-lignin flax seed oil.
>
>So, you think low/regular-lignan FSO's safer for most cancer patients?
>
>Any clinical/practical implications re: resveratrol and curcumin.
>My impression is that they're powerfully cancer-healing, and I thought
>they were indicated for the vast majority of cancer patients.
[Non-text portions of this message have been removed]
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